Pathology I - Session 4

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Define Infectious Disease

page 75

Any Dz caused by an invasion of a pathogen which grows and multiplies in the body.

What are prions?

page 76

Modified host protiens.
Affect the nervous system.

What are viruses?

page 76

Infectious agents that rely on the hosts metabolic machinery for replication.
They inject their DNA into a cell, causing the cell to make copies of the virus.

What are Bacteriophages, Plasmids and Transposons?

page 76

Mobile genetic agents that infect bacteria making them either more virulent or more resistant to antibodies

What are bacteria?

page 76

Single cell organisms that lack a true nucleus, carry only one circular chromosome, have a cell wall & membrane, multiply by binary fision and are classified as either: Cocci (round), Bacilli (rod) and Spirochetes (spiral)

What are Rickettes, Chlamydiae, Mycoplasmas?

page 76

Transmitted mostly by insects, these are like bacteria but missing certain structures or organelles.

What are Fungi?

page 76

Produce spores, asexual at times.

What are Protozoa?

page 76

Mobile, single cell organisms that replicate within the cell or urogenital system, intestines or blood. Tranmitted via fecal-oral route or by blood sucking insects.

What are Helminths?

page 76

Parasitic worms

What are Ectoparasites?

page 76

Bugs that attach to and live on the skin. (ie Bed bugs)

Define Pathogenecity.

page 77

The ability of the infectious agent to establish itself in a host and cause disease.

What is Virulence?

page 77

The measure of strength of pathogenecity

Describe Low Virulence.

page 77

Relies on person to person contact to spread.

Describe high virulence.

page 77

Can be spread by many means.

What are Virulence Factors?

page 77

The ability of the organism to produce symptoms.

What are Pili?

page 77

Appendages that allow bacteria to adhere to mucosal surfaces.

What are Toxins (regarding virulence factors) ?

page 77

Potent molecules secreted or released from bacteria.
(ie Tetanus, Botulism)

What is a cell capsule?

page 77

Protective outer surfaces that allow bacteria to avoid phagocytosis by non specific host defenses.

What is an Infective Does?

page 77

The number of bacteria required to causes disease.

What are some ways that Infectious Agents cause disease?

page 77

Kill hosts cells directly
Release enzymes that kill host cells directly
Trigger a response in the host that causes the host injury.

What is the pathogen Reservoir?

page 78

The carrier or source host of a disease.

What are 3 types of Reservoirs?

page 78

Human
Animal (#1 = Pig)
Non-animal (soil, dust, water)

What are 4 ways pathogens escape from the reservoir?

page 78

Respiratory tract
Gastrointestinal tract
Genitourinary tract
Open lesions

What are 3 Human-to-Human modes of disease transmission?

page 78

Direct sexual contact
Fecal - Oral
Inhalation

How many types of cold viruses have been identified thus far?

page 78

254

What are 3 Non-human to Human modes of disease transmission?

page 79

Soil
Water
Animal

What are 4 ways organisms gain entry into the host?

page 79

Skin
Respiratory Tract
Gastrointestinal Tract
Genitourinary Tract

What is Incubation?

page 80

The time between organism transmission to the beginning of symptoms in the host.

What are some Host Factors in regards to the spread of microbes within the host?

page 80

Age
Number of T-cells
Concentration of Pathogen
Duration of exposure
Health of Host

Do microbes spread more in Cool & Dry or Warm & Moist environments?

page 80

Warm & Moist baby, yeah!

What are 2 tissue planes in which microbes spread throughout the body?

page 80

Meninges
Aponeurosis

What happens to blood when there is too much bacteria within?

page 80

Becomes septic (too much acidity)

How can LMT's prevent the spread of disease?

page 81

Wash Hands
Clean sheets every client
Do laundry regularly
Clean lotion bottle every client
Cut nails
Keep room clean (carpet, sinks, bathroom)
Proper ventilation (clean air filters)
Dont work ill clients
Dont work when ill.
Beware of lesions

How is substance abuse diagnosed?

page 92

If the patients life has been disrupted by substance use.

What are the faxctors used to identify substance abuse?

page 80

Persistant use that results in failure to fulfill major obligations at work.
Recurrent use in physically hazardous situations.
Repeated legal problems related to substance abuse
Persistent use in spite of continued problems caused by use.

What are the qualifiers that identify susbstance dependance?

page 93

Withdrawal
Tolerance
A recurring desire to cutback
Large amounts of time involved with substance use.
Withdrawal from former activities.
Persistent use despite awareness of problem.

What is the difference between Substance Abuse and Substance Dependance.

page 93

Victim is aware of the problem with abuse, but is unable to stop use with dependance.


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