Micro-Viral

Live attenuated vaccines

MMR
Sabin polio (oral)
VZV
yellow fever
smallpox

Killed vaccines

"RIP Always"
Rabies
Influenza
Polio (Salk)
Hep A

DNA Viruses (7)

"HHAPPPPy"
Hepadna
Herpes
Adeno
Pox
Parvo
Papilloma
Polyoma

All DNA viruses are double-stranded except:

Parvovirus (single-stranded)

All DNA viruses are icosahedral except:

pox

All DNA viruses replicate in the nucleus except:

Pox

All RNA viruses are single-stranded except:

Reo
(dsRNA)

Naked viruses
3 RNA, 4 DNA

"CPR and PAPP"
Calici
Picorna
Reo
Parvo
Adeno
Papilloma
Polyoma

All RNA viruses replicate in the cytoplasm except

influenza
retroviruses

RNA viruses that are SS+

Calici
Flavi
Toga
Retro
Corona
Picorna

RNA viruses that are SS-

"Always Bring Polymerase Or Fail Replication Horribly"
Arena
Bunya
Paramyxo
Orthomyxo
Filo
Rhabdo
HDV

Picorna Viruses (5)

PERCH
Polio
Echo
Rhino
Coxsackie
Hep A

Disease caused by Parvo B19

1. Aplastic crisis in sickle cell patients (destroys erythroid precursors in BM)
2. Fifth disease (erythema infectiosum) with "slapped cheeks" rash
3. In pregnant women can cause hydrops fetalis and SAB

Slow virus infections (2)

1. Subacute sclerosing panencephalitis - from measles
2. Progressive multifocal leukoencephalopathy from JC polyoma virus

SSPE

-Caused by persistent infection with altered measles virus (no M protein)
-Asymptomatic for several years, then neuro manifestations in childhood/teens
-Slowly progressive and usually fatal.

Progressive multifocal leukoencephalopathy

-Cause is JC virus (polyoma)
-Infects oligodendrocytes causing demyelination
-Often assoc. with leukemia or lymphoma or with immunodeficiency