Tooth Development

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Teeth are composed of 4 types of tissue?

Enamel
Dentin
Pulp
Cementum

Enamel

Calcified
White layer

Dentin

Calcified
Crown to Root

Pulp

Uncalcified
Nerve, blood vessels, soft

Cementum

Calcified
Smallest layer

Tooth Development begins with the interaction of ___________&_________?

Oral Epithelial cells
Mesenchymal cells

Later _____________cells aid in tooth development?

Neural Crest cells

Oral epithelial cells come from?

Ectoderm

The dental lamina begins to form in which week of development?

5th week

Tooth development begins which week?

7th week (tooth buds)

What are the two major events in tooth development?

Morphodifferentiation
Cytodifferentiation

Morphodifferentiation

Dental Lamina-sheet of oral epithelium that grows down into the underlying ectomesenchyml

Oral epithelium cells form?

Enamel Organ

Enamel organ form?

Enamel

Mesenchymal cells form?

dental papilla

Dental Papilla form?

dentin and pulp

Neural Crest cells

-migrate to the jaws
-integrate w/enamel organ
-integrate w/dental papilla

Neural Crest Cells

Aid in tooth development

Cytodifferentiation

Cells differentiate into specific tissue forming cells

Ameloblasts

Enamel forming cells

Odontoblasts

Dentin forming cells

Cementoblasts

Cementum forming cells

Fibroblasts

Pulp forming cells

The first stage of tooth development; formation of dental lamina?

Morphodifferentiation

Dental Lamina

forms the 20 Primary teeth and 12 permanent molars

20 areas of enlargement occur along the _________

Dental lamina

Successional lamina

forms the 20 permanent teeth that replace the primary teeth

Dental Lamina remains active in the _____regions of the mouth until about age_____ with the formation of the ______.

Posterior, 15, 3rd molars

The 12 posterior molars develop from the _____

general lamina

Stages of tooth development

1. Bud Stage
2. Cap Stage
3. Bell Stage

Charac. of the Bud Stage of tooth development.

Rounded, unspecialized, localized growth surrounded by mesenchyme

Charac. of the Cap Stage of tooth Development.

Concave surface develops epithelial cells become the enamel organ

The enamel organ comes from which stage of tooth development?

Cap Stage

What forms the dental Papilla?

Mesenchyme

Cap stage has 2 features

1. Enamel Organ
2. Dental Papilla

4 charac. of enamel organ

-outer enamel epithelium OEE
-Inner enamel epithelium IEE
-Stratum intermedium
-Stellate reticulum

outer enamel epithelium

outside covers enamel organ 1 cell layer of cubodial cells

Inner enamel epithelium

1 cell layer of cubodial cells will become ameloblast

Stratum intermedium

2-3 cell layer thick, flat squamous cells, lie above the inner enamel epithelium, assist in the formation of enamel

stellate reticulum

Star shaped, supporting cells that fill the bulk of the enamel organ

Dental papilla

-composed of densley packed fibroblasts
-influencing bud stage to develop into cap and bell stage
-Cells at the periphery differentiate into odontoblasts that will produce dentin

Enamel and Dentin production happens in which stage of tooth development?

Bell stage

Inner Enamel Epithelium becomes what?

Ameloblast

Dental Papilla

Cell closest to the IEE differentiate and become odontoblast-center cells that become dental pulp

Dental Follicle

From mesenchyme, surrounds the developing tooth germ, provides cells that will form cementum, PDL, and Alveolar bone

Cervical loop

Junction between inner/outer enamel epithelium

Ameloblast differentiate first from the _____

IEE

A basement membrane develops between the 2 cell layers and eventually becomes the

DEJ

_______precedes______;
_______is formed before_____

Dentinogenesis precedes Amelogenesis; Dentin is formed before enamel

Dentinogenesis

1st Cells of the IEE become ameloblast but remain dormat.
2nd Cells of the dental papilla become odontoblasts; they begin forming a matrix of collagen fibers called predentin.

All dentin and enamel formation begins at the

DEJ

Odontoblasts develop an elongated process that lies within_______

Dentinal Tubules

Dentin is a _____Tissue that continues to be produced throughout lifetime.

Vital-the dentinal processes are living tissues.

______is sensitive?

Dentin

Amelogenesis

1st area formed is cusp tip and later they grow together

______form at the end of the ameloblasts taht are producing enamel?

Tomes Processes

Time between amelogen deposition and mineralization is ______

Short

Enamel is ______tissue.

NonVital

Mature enamel is ___% mineralized?

95

Amelogen---Enamelin-----_____?

Enamel

REE

Reduced Enamel Epithelium

REE is formed by?

-Fusion of the ameloblasts with the cuticle
-Parts of the enamel epithelium
-Stellate reticulum

The REE remains on the surface of the enamel until the tooth_____?

Erupts

Root Formation

The place where the IEE and OEE meet is called the cervical loop.

The cervical loop becomes known as _______.

Hertwigs epithelial root sheath

The point where root formation begins?

Hertwigs epithelial root sheath.

2 Layers of the Hertwigs epithelial root sheath?

1 outer layer
2 inner layer

Inner layer

Develp from ameloblast (IEE), induce the odontoblast of the dental papilla to form dentin that continues down from the crown to the root.

outer layer

forms intermediate cementum (acellular) that seals out the root surface

After the root sheath deposits intermediate cementum, it breaks down and forms?????

Epithelial rests

The epithelial rests move away from the root into the _______area?

Follicular

Mesenchymal cells from the _______ contact the root surfaces and differentiate into_____?

Follicle; cementoblasts

Cementum near the crown is _____?

Thinner and Acellular

Cementum at the tooth apex is

Thicker and more cellular

The primary function of the cementum is_____________?

Attachment of the PDL

______produce cementoid. After it calcifies it is called?????

Cementoblasts; cementum


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