|
GABAergic |
inhibt activity in muscles |
|
cholinergic |
excite the worms muscles |
|
administration |
ORAL, |
|
blocks ACH |
piperazine |
|
depolazirers...induce Ach..block ACHase |
pyrantel pamoate + metrifonate |
|
increase ca+2 perm |
praziquantel |
|
microtuble polymerization and formation |
alberndazole or mebendazole |
|
stimulate GABA |
ivermectin |
|
ascarisasis (round worm) |
alberndazole or mebendazole |
|
Clonorchiasis (Oriental liver fluke) |
Praziquantel* |
|
Diphyllobothriasis (Fish tapeworm) |
Praziquantel* |
|
Enterobiasis (Pinworm Disease) |
Mebendazole |
|
Filariasis (Elephantiasis) |
Diethylcarbamazine Citrate* |
|
Hookworm Disease (Necator Americanus) |
Mebendazole |
|
Onchocerciasis (River Blindness) |
Ivermectin* |
|
Strongyloidiasis (Threadworm Disease) |
Ivermectin |
|
Taeniasis (Pork/Beef Tapeworm) |
Praziquantel*; Niclosamide* |
|
Trichuriasis (Whipworm Disease) |
Albendazole; Mebendazole |
|
Albendazole |
Elevated liver enzymes (long-term use) |
|
Diethlycarbamazine Citrate |
give antihist first few days |
|
Ivermectin |
Corneal opacity, various types of eye lesions |
|
Mebendazole |
IV rnxs can increse with cimitidine |
|
Praziquantel |
liver enz raised, Parasite destruction in the eye may cause irreparable damage); Spinal no physical acitivy...sleepy |
|
DO NOT USE IN |
preg, young childrens, |





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