anti-helminths

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GABAergic

inhibt activity in muscles

cholinergic

excite the worms muscles

administration

ORAL,
Thiabendazole is topcial and oral

blocks ACH

piperazine

depolazirers...induce Ach..block ACHase

pyrantel pamoate + metrifonate

increase ca+2 perm

praziquantel

microtuble polymerization and formation

alberndazole or mebendazole

stimulate GABA

ivermectin

ascarisasis (round worm)

alberndazole or mebendazole

Clonorchiasis (Oriental liver fluke)

Praziquantel*

Diphyllobothriasis (Fish tapeworm)

Praziquantel*

Enterobiasis (Pinworm Disease)

Mebendazole

Filariasis (Elephantiasis)

Diethylcarbamazine Citrate*

Hookworm Disease (Necator Americanus)

Mebendazole

Onchocerciasis (River Blindness)

Ivermectin*

Strongyloidiasis (Threadworm Disease)

Ivermectin

Taeniasis (Pork/Beef Tapeworm)

Praziquantel*; Niclosamide*

Trichuriasis (Whipworm Disease)

Albendazole; Mebendazole

Albendazole

Elevated liver enzymes (long-term use)

Diethlycarbamazine Citrate

give antihist first few days
-allergic rnxs
-HTN

Ivermectin

Corneal opacity, various types of eye lesions

Mebendazole

IV rnxs
Convulsions in young children

can increse with cimitidine

Praziquantel

liver enz raised,
neurological abnromalities

Parasite destruction in the eye may cause irreparable damage); Spinal

no physical acitivy...sleepy

DO NOT USE IN

preg, young childrens,


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