Test Yourself On Cholesterol, Lipid digest/absorb,lipoprotein metab Flashcards

Matching (20) Match items in column A to column B

Column a	Column b
1. They don't JUST inhibit production of cholesterol. When there is less cholesterol released from liver, the LDL receptors are upregulated, resulting in MORE LDL being taken up by cells and out of blood.	A. Pancreatic lipase (and colipase)
Answer: You said: Correct:
2. an ester of cholesterol. The ester bond is formed between the carboxylate group of a fatty acid and the hydroxyl group of cholesterol. Cholesteryl Esters have a lower solubility in water than Cholesterol and, in other words, are more hydrophobic. <b>They are associated with atherosclerosis.</b>	B. Does most cholesterol in the body come from dietary cholesterol?
Answer: You said: Correct:
3. bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption in the ileum. (>95% of bile salts are normally resorbed via portal system)	C. Overall general idea of cholesterol biosynthesis
Answer: You said: Correct:
4. refers to the circulation of biliary acids from the liver, where they are produced and secreted in the bile, to the small intestine, where it aids in digestion of fats and other substances, back to the liver.	D. Cholesteryl Ester
Answer: You said: Correct:
5. Membrane constituent, precursor to bile acids, steroid hormones, and Vitamin D.	E. How statins work
Answer: You said: Correct:
6. Isoprene is a precursor molecule to many things, including dolichol, CoenzymeQ, Vitamin A, and Vitamin E Its synthesis is also blocked by statins..	F. What is the ultimate precursor to cholesterol?
Answer: You said: Correct:
7. 1) More easily broken down by pancreatic lipase. (better substrates) 2) Can be infused parenterally (totally bypassing digestive system) 3) Do not go through the carnitine shuttle, so they're more easily B-oxidized.	G. What is the main purpose of micelles?
Answer: You said: Correct:
8. NO. Most of it is made bythe body. Dietary cholesterol is only fractionally absorbed.	H. HMG CoA Reductase
Answer: You said: Correct:
9. 1) Made in the liver and stored/concentrat ed in gallbladder. 2) Is a mix of bile salts, phospholipids, and cholesterol stabilized in micelles and other aggregate structures. 3) Has a polar face and a hydrophobic ring system. Because of this it's detergent by nature.	I. Trace the path of chylomicrons
Answer: You said: Correct:
10. Catalyzes the rate-limiting step in cholesterol biosynthesis. The target for statins.	J. Isoprene (Isoprenoids)
Answer: You said: Correct:
11. Converts acetoacetyl CoA into 3OH3CH3glutarylCoA (similar to ketogenesis) 2nd step in cholesterol synth	K. Common bile duct
Answer: You said: Correct:
12. Formed in the enterocytes --> released into lacteals --> bloodstream	L. First step in cholesterol synthesis?
Answer: You said: Correct:
13. Linosterol It's even more atherosclerotic than cholesterol!	M. Enterohepatic Circulation of Cholesterol
Answer: You said: Correct:
14. Coats fat coming in from stomach, increases surface area. Coat surface – stabilize fat droplets, disperse the lipids somewhat	N. Why are medium chain fatty acids good to use in people with impaired digestive function?
Answer: You said: Correct:
15. Converts acetyl-CoA to acetoacetyl CoA in the mevalonate pathway. (1st step in cholesterol synth)	O. What is the first steroid in the pathway?
Answer: You said: Correct:
16. Is a transport duct for bile from liver (from gallbladder) and pancreatic juice from pancreas.	P. Thiolase
Answer: You said: Correct:
17. A) Acetyl CoA --> HMG CoA (HMG CoA synthase) B) HMG-CoA --> mevalonate RATE LIMITING STEP!!! HGM-CoA Reductase C) Basic 5 carbon building block: mevalonate --> isopentenyl PP D) Polymerization (5C->10C->15C->30C) E) Cyclization (squalene to lanosterol) F) Sterol modification (lanosterol --> cholesterol)	Q. HMG CoA Synthase
Answer: You said: Correct:
18. Hydrolyzes ester bonds of triglyceride to produce free fatty acid and 2 monoglycerol (leaves one fatty acid on) Requires colipase	R. Cholestyramine
Answer: You said: Correct:
19. Acetic acid	S. Bile
Answer: You said: Correct:
20. Acetyl CoA to acetoacetyl CoA via thiolase.	T. What are some uses for cholesterol?
Answer: You said: Correct:

Related Flashcards

Cholesterol, Lipid Digest/absorb,lipoprotein Metab

Test Results

Your Score

Matching (20) Match items in column A to column B

Done with this test?

Related Flashcards

Cholesterol, Lipid Digest/absorb,lipoprotein Metab

Add to Folders

Upgrade to Cram Premium

Test Results

Your Score

Matching (20) Match items in column A to column B

Done with this test?